five

Breast cancer derived Evs cause liver fibrosis. [II]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE262917
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资源简介:
breast cancer derived Evs carried NT5C2 to liver tissue, which causes inosine accumulation in liver. High inosine level suppressed ADAR1-P150 protein level and decreased global A-I editing level. Fibronectin-1 displayed a higher mRNA level due to the reduction of splicing sites' editing. Overall, breast cancer derived EVs cause liver fibrosis. mice recived inosine intraperitoneal injection and control.
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2025-01-01
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