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Systematic characterization of the composition and dynamics of processing body-associated mRNAs

NIAID Data Ecosystem2026-05-10 收录

mRNA翻译调控

RNA降解机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE279285 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-09-16

mRNA翻译调控

发育时序调控

Maternal mRNAs are synthesized during oogenesis to initiate the development of future generations. Some maternal mRNAs are determinants of somatic or germline fate and must be translationally represse

NIAID Data Ecosystem30

GCN2 suppresses TOP mRNA translation via LARP1

mRNA翻译调控

营养应激响应

La-related protein 1 (LARP1) has been identified as a key translational inhibitor of terminal oligopyrimidine tract (TOP) mRNAs downstream of the nutrient sensing protein kinase complex, mTORC1. LARP1

NIAID Data Ecosystem30

The fission yeast MTREC complex targets CUTs and unspliced mRNAs to the nuclear exosome [RNA-Seq]. Schizosaccharomyces pombe

RNA降解机制

转录后质量控制

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome, however, the way they are recognized and targeted to the exosome is not fully understood. The recently identified Schiz

NIAID Data Ecosystem20

eIF4F-Independent mRNA Translation, Coots et al.

mRNA翻译调控

蛋白质印迹

Raw images of western blots.

NIAID Data Ecosystem30

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome. Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome

RNA结合蛋白调控

RNA降解机制

Pumilio paralogs, PUM1 and PUM2, are sequence-specific RNA-binding proteins that are essential for vertebrate development and neurological functions. PUM1&2 function to negatively regulate gene expres

NIAID Data Ecosystem20

Systematic characterization of the composition and dynamics of processing body-associated mRNAs

资源简介：

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