Synthesis of Substituted Furan/Pyrrole-3-carboxamides through a Tandem Nucleopalladation and Isocyanate Insertion
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https://figshare.com/articles/dataset/Synthesis_of_Substituted_Furan_Pyrrole-3-carboxamides_through_a_Tandem_Nucleopalladation_and_Isocyanate_Insertion/3611457
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资源简介：
Access to furanyl- and pyrrolyl-3-carboxamides
from readily available
3-alkyne-1,2-diols and 1-amino-3-alkyn-2-ols using isocyanate as amido
surrogate is demonstrated. The approach constitutes a successful unprecedented
combination of heteropalladation and isocyanate insertion, a new avenue
for novel amide bond constructions. The mechanism likely involves
a 6-membered oxaaminopalladacycle as the key intermediate.
创建时间：
2016-08-29
