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Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal Structure of 11b-HSD1 in Complex with Triazole Inhibitor Descriptor: 3-[1-(4-fluorophenyl)cyclopropyl]-4-(1-methylethyl)-5-[4-(trifluoromethoxy)phenyl]-4H-1,2,4-triazole, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Wang, Z, Liu, J, Sudom, A, Walker, N.P.C. Deposit date: 2008-05-16 Release date: 2008-10-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Bioorg.Med.Chem., 16, 2008
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2008-05-16
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