Experimental dataset (Hilger et al. Effect of canagliflozin on intracellular uropathogenic E. coli counts and α-hemolysin function)

Supporting data for the quantification of intracellular uropathogenic E. coli strains or Salmonella Typhimurium strain LT2 in different eukaryotic cell lines in the presence or absence of SGLT2 inhibitors (colony forming units) analysis of bacterial growth in the presence or absence of SGLT2 inhibitors (OD values) analysis of eukaryotic cell viability and proliferation in the presence or absence of SGLT2 inhibitors utilizing the natural reducing power of living cells (Alamar blue assay, fluorescence values) analysis of erythrocyte lysis caused by sterile filtered bacterial culture supernatants treated with SGLT2 inhibitors (OD values) A detailed description of the relevant experiments can be found in the publication by Hilger et al. (2026) Canagliflozin reduces the recovery of intracellular uropathogenic Escherichia coli from uroepithelial cells and affects α-hemolysin function. Scientific Reports