Ground state of pluripotency cannot be maintained in mouse embryonic stem cells upon prolonged inhibition of GSK3. Mus musculus

We compare gene expression changes in mESCs culture in serum/LIF or 2i/LIF which favour the ground state pluripotency. Published RNASeq data where compared with newly generated data set in order to indentify transciptional signatures associated with pluripotency of mouse ES cells Overall design: Examination of dynamic gene expression in mouse ES cells culture in convetional media (serum/LIF) and in 2i/LIF which favour the gorund state pluripotency