Uptake of exogenous phospholipids by Borrelia burgdorferi

The Lyme disease pathogen Borrelia burgdorferi can take up environmental phospholipids for membrane biosynthesis. These phospholipids include those also produced de novo by the bacterium (PC and PG) and some that are mammalian-like. We examined the effect of exogenous phospholipids on gene expression. Overall design: RNAseq analysis of B. burgdorferi cells grown in standard medium or medium supplemented with extra phospholipids.