Single-cell RNA sequencing of Cd45+ adventitial cells from mice at steady state or treated with AngiotensinII
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
下载链接：
http://data.iscr.ac.cn/Article?id=6f1b2f4a878c6456d3d8a632bd3e63d2
下载链接
链接失效反馈官方服务：
资源简介：
Here we show, that arterial macrophages derive predominantly from YS EMPs, which give rise to a transcriptionally distinct cluster of macrophages with mainly homeostatic and anti-inflammatory properties in steady state as well as in response to AngII inflammation. In adult mice, these EMP-derived macrophages persist for long periods of time, but decreas in absolute numbers in senescence without compensation by BM-derived progenitors. EMP-derived macrophages expressed high levels of homeostatic genes such as Lyve-1, which links them to physiological functions in arteries.
提供机构：
Technical University of Munich
创建时间：
2022-02-20
