The prognosis for HCC is very poor, mainly because early diagnosis was often not feasible. Serum AFP as a diagnostic tool for early HCC has significant limitations. Intestinal microbial variation is closely associated with liver injury and chronic inflammatory, and ultimately promotes HCC development by intestinal microbiota-liver axis. This study was the first to identify intestinal microbial characteristics in clinical HCC patients.. Liver Cancer Diagnosis

The prognosis for HCC is very poor, mainly because early diagnosis was often not feasible. Serum AFP as a diagnostic tool for early HCC has significant limitations. Intestinal microbial variation is closely associated with liver injury and chronic inflammatory, and ultimately promotes HCC development by intestinal microbiota-liver axis. This study was the first to identify intestinal microbial characteristics in clinical HCC patients.