Zelda determines chromatin accessibility during the Drosophila maternal-to-zygotic transition

ChEBI2015-08-06 更新2026-07-12 收录

发育表观遗传学

染色质可及性调控

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Zelda determines chromatin accessibility during the Drosophila maternal-to-zygotic transition

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2015-08-06

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组蛋白甲基化分析

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Embryos with maternal mutation of the H3K9 methyltransferase SETDB1 die before implantation. We tested the role of maternal SETDB1 in the timely processes of the preimplantation stage embryo. Using si

NIAID Data Ecosystem30

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干细胞重编程

染色质可及性调控

Chemical induction of pluripotency (CIP) is an ideal way to reprogram cell fate, but remains poorly understood. Here we report the development of an efficient CIP protocol and the chromatin accessibil

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发育表观遗传学

心肌细胞分化

Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play

NIAID Data Ecosystem40

Zelda determines chromatin accessibility during the Drosophila maternal-to-zygotic transition

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