Crystal structure of NS3/4A protease variant A156T in complex with MK-5172
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Crystal structure of NS3/4A protease variant A156T in complex with MK-5172 Descriptor: (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di oxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadec ino[11,12-b]quinoxaline-8-carboxamide, NS3 protease, NS4A protein, ... Authors: Schiffer, C.A, Romano, K.P. Deposit date: 2011-07-11 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
创建时间：
2011-07-11
