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Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6l2q
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Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor Descriptor: (2S,3R)-2-azanyl-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-3-oxidanyl-butanamide, 1,2-ETHANEDIOL, Threonine--tRNA ligase, ... Authors: Guo, J, Chen, B, Zhou, H. Deposit date: 2019-10-05 Release date: 2020-01-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping. Eur.J.Med.Chem., 187, 2019
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2019-10-05
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