Scheltens scores and lesion distribution assessment (LDA) scores of the CADASIL family members.

1 0 = absent; 1 = 0 to 5 mm; 2 = > 5 mm
2 0 = absent; 1 = up to five lesions of <3mm diameter; 2 = six or more lesions of <3mm; 3 = up to five lesions 4 to 10 mm in diameter; 4 = six or more lesions of 4 to 10mm; 5 = one or more lesions 10mm in size; and 6 = confluent hyperintensity
3 0 = absent, 1 = <5 lesions, 2 = 5–10 lesions, 3 = >10 lesions
4 0 = absent, 1 = mild, 2 = moderate, 3 = severe (sulcal, cerebellar folia prominence, enlargement of ventricles, brainstem size)
Scheltens scores and lesion distribution assessment (LDA) scores of the CADASIL family members.