​​​Developing biomarkers incorporating high throughput RNA, DNA, small RNA sequencing and protein expression in Inflammatory Bowel Disease using formalin-fixed, paraffin-embedded (FFPE) tissue samples.​​

This dataset includes RNA-seq data from ileal and colonic biopsies at time of diagnosis for treatment-naive, uncomplicated Crohn's disease (CD) patients and matched controls. This is includes 56 CD patients each for ileal and colonic tissue and for controls, 46 colonic samples and 45 ileal samples. Clinical characteristics such as development of complications, disease remission, or progression to surgery were recorded with a mean follow-up of 6 years. RNA-seq data was generated from biopsies at time of diagnosis. Retrospective chart review was used to obtain clinical characteristics. Gene expression was compared and modeled between diseased and non-diseased cases and complicated and uncomplicated cases. NOTE FROM SUBMITTER: Due to patient privacy concerns, we plan to upload raw fastq files to dbGaP.