AneuX morphology database

The AneuX morphology database is an open-access, multi-centric database containing 3D geometries of 750 intracranial aneurysms curated in the context of the AneuX project (2015-2020). The database combines data from three different projects (AneuX, @neurIST and Aneurisk) standardized using a single processing pipeline. The code to process and view the 3D geometries is provided under this public repository: https://github.com/hirsch-lab/aneuxdb

The database at a glance:

750 aneurysm domes (surface meshes)

668 vessel trees (surface meshes)

3 different data sources (AneuX, @neurIST, Aneurisk)

3 different mesh resolutions (original resolution, 0.01mm² and 0.05mm² target cell area)

4 different cut configurations (including planar and free-form cuts)

5 clinical parameters (aneurysm rupture status, location and side; patient age and sex)

170 pre-computed morphometric indices for each of the aneurysm domes

Terms of use / License:

The data is provided "as is", without any warranties of any kind. It is provided under the CC BY-NC 4.0 license, with the additional requirements (A) that the use of the database is declared using the sentence below (you can omit the URLs), and (B) to cite our peer reviewed journal article below.

[This project] uses data from the AneuX morphology database, an open-access, multi-centric database combining data from three European projects: AneuX project (www.aneux.ch), @neurIST project (www.aneurist.org) and Aneurisk (http://ecm2.mathcs.emory.edu/aneuriskweb/index).

In accordance with the terms of use, please cite the following journal article when referring to our dataset.

Juchler, Schilling, Bijlenga, Kurtcuoglu, Hirsch. Shape trumps size: Image-based morphological analysis reveals that the 3D shape discriminates intracranial aneurysm disease status better than aneurysm size. Frontiers in Neurology (2022), DOI: 10.3389/fneur.2022.809391

The AneuX morphology database contains parts (geometric models, clinical data) of the publicly available Aneurisk dataset released under the CC BY-NC 3.0 license (which is compatible with the license used here). Like all geometric models in this database, the Aneurisk models were preprocessed using the same procedure. See here for a description.

Funding and authorizations 

The AneuX project

Data collection in accordance with @neurIST protocol v5

Ethics autorisations Geneva BASEC PB_2018‐00073

Supported by the grant from the Swiss SystemsX.ch initiative, evaluated by the Swiss National Science Foundation

@neurIST project

Data collection in accordance with @neurIST protocol v1

Ethics autorisations AmsterdamMEC 07-159, Barcelona2007-3507, Geneva CER 07-056, Oxfordshire REC AQ05/Q1604/162, Pècs RREC MC P 06 Jul 2007

Supported by the 6th framework program of the European Commission FP6-IST-2004–027703

Acknowledgments:

The AneuX project was supported by SystemsX.ch, and evaluated by the Swiss National Science Foundation (SNSF). This database would not be possible without the support of the Zurich University of Applied Sciences (ZHAW) and University Hospitals Geneva (HUG).

We thank the following people for their support and contributions to the AneuX morphology database.

From the AneuX project (in alphabetical order):

Daniel Rüfenacht

Diana Sapina

Isabel Wanke

Karl Lovblad

Karl Schaller

Olivier Brina

Paolo Machi

Rafik Ouared

Sabine Schilling

Sandrine Morel

Ueli Ebnöther

Vartan Kurtucuoglu

Vitor Mendes Pereira

Zolt Kuscàr

From the @neurIST project (in alphabetical order)

Alan Waterworth

Alberto Marzo

Alejandro Frangi

Alison Clarke

Ana Marcos Gonzalez

Ana Paula Narata

Antonio Arbona

Bawarjan Schatlo

Daniel Rüfenacht

Elio Vivas

Ferenc Kover

Gulam Zilani

Guntram Berti

Guy Lonsdale

Istvan Hudak

James Byrne

Jimison Iavindrasana

Jordi Blasco

Juan Macho

Julia Yarnold

Mari Cruz Villa Uriol

Martin Hofmann-Apitius

Max Jägersberg

Miriam CJM Sturkenboom

Nicolas Roduit

Pankaj Singh

Patricia Lawford

Paul Summers

Peer Hasselmeyer

Peter Bukovics

Rod Hose

Roelof Risselada

Stuart Coley

Tamas Doczi

Teresa Sola

Umang Patel

From the Aneurisk project (list from AneuriskWeb, in alphabetical order):

Alessandro Veneziani

Andrea Remuzzi

Edoardo Boccardi

Francesco. Migliavacca

Gabriele Dubini

Laura Sangalli

Luca Antiga

Maria Piccinelli

Piercesare Secchi

Simone Vantini

Susanna Bacigaluppi

Tiziano Passerini