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Crystal Structure of PRMT4 with Compound YD1113

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Protein Data Bank Japan2024-02-21 更新2026-04-19 收录
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Crystal Structure of PRMT4 with Compound YD1113 Descriptor: 5'-S-[2-(benzylcarbamamido)ethyl]-5'-thioadenosine, GLYCEROL, Histone-arginine methyltransferase CARM1, ... Authors: Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2023-02-03 Release date: 2023-12-13 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.49 Å) Cite: A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors. Acta Pharm Sin B, 13, 2023
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2023-02-03
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