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Functional Antagonism Between CELF and Mbnl Proteins in Cytoplasm and Nucleus [CLIP-seq]. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA262628
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The CUG-BP and ETR-3-like factor 1 (Celf1) RNA binding protein plays an important role in heart and muscle development, and is over-expressed in the disease myotonic dystrophy. Celf1 has known roles in regulation of RNA splicing, RNA stability, and protein translation. To identify transcriptome-wide targets of the Celf1 protein, we performed CLIP-seq against Celf1 using the 3B1 antibody, in myoblasts, heart tissue, and muscle tissue. Overall design: CLIP-Seq was performed against Celf1 in mouse muscle, heart, and C2C12 mouse myoblasts.
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2014-09-30
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