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Crystal structure of human MMP-2 catalytic domain in complex with inhibitor

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Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7xjo
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Crystal structure of human MMP-2 catalytic domain in complex with inhibitor Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... Authors: Kamitani, M, Mima, M, Takeuchi, T. Deposit date: 2022-04-18 Release date: 2022-06-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Aryloxyphenyl-Heptapeptide Hybrids as Potent and Selective Matrix Metalloproteinase-2 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis. J.Med.Chem., 65, 2022
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2022-04-18
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