HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680 Descriptor: CHLORIDE ION, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, SODIUM ION, ... Authors: Salah, E, Ugochukwu, E, Elkins, J.M, Barr, A.J, Shrestha, B, Savitsky, P, Mahajan, P, Muniz, J.R.C, Yue, W.W, Chaikuad, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2010-11-18 Release date: 2010-12-01 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Crystal Structures of Abl-Related Gene (Abl2) in Complex with Imatinib, Tozasertib (Vx-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J.Med.Chem., 54, 2011
创建时间：
2010-11-18
