Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=61390f492836d470bc9933a8c03324a2
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资源简介：
Mapping the transcriptional landscape of human embryonic skeletogenesis at single-cell resolution during limb bud and primary ossification center (POC) formation. We found significant heterogeneity of stromal cells within the limb bud mesenchyme that specified proximal-distal and anterior-posterior patterning. Embryonic skeletal stem and progenitor cells first appeared during POC formation, which were highly enriched by CADM1 expression and could differentiate into osteoblasts, chondrocytes and periosteal mesenchymal stromal cells.
提供机构：
the Fifth Medical Center of the PLA General Hospital
创建时间：
2022-02-20
