The structural basis of aldo-keto reductase 1C3 inhibition by 17alpha-picolyl and 17(E)-picolinylidene androstane derivatives

Protein Data Bank Japan2025-09-17 更新2026-06-30 收录

下载链接：

https://pdbj.org/mine/summary/8rrj

下载链接

链接失效反馈

官方服务：

资源简介：

The structural basis of aldo-keto reductase 1C3 inhibition by 17alpha-picolyl and 17(E)-picolinylidene androstane derivatives Descriptor: (3~{Z},8~{R},9~{S},10~{R},13~{S},14~{S},17~{R})-3-hydroxyimino-10,13-dimethyl-17-(pyridin-2-ylmethyl)-2,6,7,8,9,11,12,14,15,16-decahydro-1~{H}-cyclopenta[a]phenanthren-17-ol, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Petri, E.T, Skerlova, J, Plavsa, J.J, Brynda, J, Ajdukovic, J.J, Bekic, S, Celic, A.S, Rezacova, P. Deposit date: 2024-01-22 Release date: 2025-05-14 Last modified: 2025-09-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The structural basis of aldo-keto reductase 1C3 inhibition by 17 alpha-picolyl and 17( E )-picolinylidene androstane derivatives. J Enzyme Inhib Med Chem, 40, 2025

创建时间：

2024-01-22