ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1
收藏NIAID Data Ecosystem2026-03-12 收录
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ENO1 (α-Enolase 1) is a key glycolytic enzyme that catalyzes the dehydratation of 2-phosphoglycerate to phosphoenolpyruvate. It also belongs to a member of the RNA degradosome of Escherichia coli and facilitates RNA degradation, but it’s currently unknown whether ENO1 possesses similar function in eukaryotes. To test this possibility,we performed RNA-seq assays expressing NTC or ENO1 shRNA, respectively. We treated PLC cells expressing NTC or ENO1 shRNA, respectively. we next performed RNA extraction and sequenced on Illumina novaseq (Homo sapiens).
创建时间:
2021-09-11



