Transcriptomic analysis of mRNA expression changes induced by RANKL expression in the murine salivary gland. Transcriptomic analysis of mRNA expression changes induced by RANKL expression in the murine salivary gland

Sequencing of mRNA isolated from salivary glands of control mice and mice overexpressing RANKL in keratin 5 (K5)-positive cells for 2 weeks. Overall design: Control (monogenic control) and K5-rtTA:TetO-RANKL mice were administered doxycycline (in food and water) at 9-weeks of age for 2 weeks to induce transgenic RANKL expression. Each RNA sample was isolated from pooled salivary gland tissues from 5 mice.