Fold-change of tissue fatty acid amide levels following a single oral treatment with PF-3845 compared to oral vehicle treatment.

Values are fold-changes compared to vehicle treatment levels in spinal cord injured (SCI) and non-injured (N.I) rats. Tissues were collected 4 hours post-oral administration of either PF-3845 (3, 10 mg/kg) or vehicle.
“Epicenter” refers to thoracic spinal cord tissue either from the site of injury from SCI rats or comparable spinal cord tissue from non-injured rats.
*p<0.05, **p<0.01, ***p<0.001 vs. vehicle-treated (Student's t-test).