Pa.FabF-C164Q in complex with ~{N}-cyclopentyl-3-methyl-1~{H}-pyrazole-5-carboxamide
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Pa.FabF-C164Q in complex with ~{N}-cyclopentyl-3-methyl-1~{H}-pyrazole-5-carboxamide Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... Authors: Georgiou, C, Brenk, R. Deposit date: 2023-02-22 Release date: 2024-01-10 Last modified: 2025-05-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Towards new antibiotics: P. aeruginosa FabF ligands discovered by crystallographic fragment screening followed by hit expansion. Eur.J.Med.Chem., 291, 2025
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2023-02-22
