Clinical and molecular risk factors in extracranial malignanat rhabdoid tumors - towards an integrated model of high-risk tumors. Clinical and molecular risk factors in extracranial malignanat rhabdoid tumors - towards an integrated model of high-risk tumors

We characterize relapse patterns in eMRT and analyzed DNA methylation of eMRT primary and relapse tissues. Using NMF-based clustering, we identify 3 subgroups of which ne subgroup displayed significantly improved survival rates. Based on the subgroups, we provide a random forest-based model to prognosticate survival. Overall design: The DNA methylation of 80 eMRT tumor samples was analyzed.