Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity

Name: Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity
Creator: 国家人口健康科学数据中心
Published: 2026-06-01 01:26:11
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中国科技资源共享网2026-06-01 更新2026-01-30 收录

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https://escience.org.cn/metadata/detail?cstrId=CSTR:17970.11.A001G.202009.435.V1.0&id=774e74221ac511e980780242ac120006:CSTR:A0006.11.A001G.202009.435.V1.0

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资源简介：

In this study, we found that myeloid PTEN can determine chemotherapy responsiveness by promoting NLRP3-dependent antitumor immunity and suggest that it might be a potential biomarker to predict the chemotherapy responses and manipulating NLRP3/IL-1might be able to overcome the chemotherapy resistance in PTEN-loss patients.

提供机构：

国家人口健康科学数据中心

创建时间：

2020-11-24