Clinical History of AIED and control patients undergoing cochlear implantation.

PTA: Pure tone average of the audiogram at 500, 1000, 2000 and 4000 Hz, (although 4000 Hz is not traditionally included, this information is important to speech perception for cochlear implantees and therefore PTA represents these four frequencies for these patients). NP: Not Performed: control subjects did not have serology for AIED performed as there was no clinical indication for such studies, HINT: Hearing in Noise Test; IT-MAIS: Infant-Toddler Meaningful Auditory Integration Scale, LVA: Large Vestibular Aqueduct; Cx26: connexin 26 gene mutation. Superscript numbers in column 1 refer to inclusion of the patient in data sets for the below figures: 1: included in analysis for figure 1; 2b & c: included in analysis for figure 2b or 2c. In one patient, all RNA was used for microarray analysis (79 y/o female, control).