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Synthesis of the Conformationally Constrained Tyrosine Analogues, (<i>R</i>)- and (<i>S</i>)-5-Hydroxy-2-aminoindan-2-carboxylic Acids

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The conformationally constrained tyrosine analogues, (R)- and (S)-5-hydroxy-2-aminoindan-2-carboxylic acids, were prepared by chromatographic separation of diastereomeric dipeptide derivatives formed from N-Boc-l-phenylalanine. Absolute configurations were assigned by X-ray crystallographic analysis.

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2016-02-25
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