Correlation analysis.

Plasma and sera samples from seronegative/healthy (SN/H, n = 45) and seropositive/chagasic (SP/C, n = 116) subjects were submitted to spectrophotometry analysis of various biomarkers of inflammation, oxidative stress, antioxidant status and cellular injury as described in Materials and Methods. Pearson's or Spearman's analysis was conducted to evaluate the strength of linear relationship between sera or plasma levels of biomarkers (among themselves) or with clinical disease category. Correlations coefficient (r) value of >0.8 was considered very strong and that of between 0.6–0.8 accepted as moderately strong [31]. “-”indicates a significant correlation at p<0.01 was not present. ND: not determined.