Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470B
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Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470B Descriptor: CALCIUM ION, Macrophage metalloelastase, N-[(2S)-3-[(R)-(4-bromophenyl)(hydroxy)phosphoryl]-2-{[3-(3'-chlorobiphenyl-4-yl)-1,2-oxazol-5-yl]methyl}propanoyl]-L-a lanyl-L-alaninamide, ... Authors: Stura, E.A, Vera, L, Beau, F, Devel, L, Cassar-Lajeunesse, E, Dive, V. Deposit date: 2012-08-24 Release date: 2013-02-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.497 Å) Cite: Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies. J.Med.Chem., 56, 2013
创建时间：
2012-08-24
