Expression regulation by Phc1 in mouse embryonic stem cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA532733
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资源简介:
Polycomb group (PcG) proteins maintain cell identity by transcriptionally silencing developmental genes during embryogenesis. Phc1 is a subunit of cPRC1 known for gene repression, in the maintenance of pluripotency. To further explore how Phc1 might regulate the pluripotency of mESCs in both PRC1-dependent and PRC1-independent manners, we performed RNA-sequencing of the wildtype, Phc1-/- and Phc1-/- + Nanog overexpression mESCs.
创建时间:
2019-04-13



