RNA-seq datasets for "Temporally Specific Gene Expression and Chromatin Remodeling Programs Regulate a Conserved Pdyn Enhancer"

This dataset contains Assay for Transposase-Accessible Chromatin (ATAC) sequencing results from rat embryonic striatal neuronal cultures treated with either vehicle (complete Neurobasal media) or potassium chloride (10mM) for 4 h. Overall design: This experiment contains 18 biological samples, each of which underwent ATAC-seq on an Illumina NextSeq500 instrument. Data are from two experiments. In the first experiment, samples were treated with neurobasal media (vehicle; samples V1, V3, V4), or 10mM KCl (samples K2, K3, K4) . The first letter of sample names denotes acute treatement (V = vehicle, K = KCl). The second digit denotes the unique replicate ID. In the second experiment, samples were treated with anisomycin (40µM) or DMSO control 30 minutes prior to depolarization with 10mM KCl. "DV" samples received DMSO followed by vehicle. "DK" sample received DMSO followed by 10mM KCl. "AK" samples received 40µM anisomycin followed by 10mM KCl. Forward and reverse paired-end reads are denoted as "R1" or "R2" in raw file names.