Concentrations of analytes in plasma and association of analytes with diagnostic groups.

Whole cohort presents results for the whole cohort and was based on all three diagnostic groups. Plasma protein levels were generally higher in AD than in MCI or control with a few exceptions. The relationship between cytokines and diagnostic groups was assessed by linear regression adjusting for age, gender, collection site and presence of the APOε4 allelle. In this analysis beta values are for the log transformed data. Key: Beta = regression coefficient (slope) on log- transformed data; 95% CI = 95% confidence interval; R2 = R2 value (coefficient of determination) after adjusting for covariates; *p<0.05.