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Cenobamate exhibit prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights

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NIAID Data Ecosystem2026-05-10 收录
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This dataset contains behavioral and immunohistochemical data from the study "Cenobamate exhibits prophylactic and therapeutic efficacy against cisplatin-induced peripheral neuropathy in rats: Behavioral and mechanistic insights." Behavioral assessmentS in cisplatin-treated rats include: - *Sensory*: mechanical allodynia (dynamic plantar aesthesiometer), cold allodynia (acetone drop test), thermal hyperalgesia (Hargreaves test) - Motor: rotarod performance and footprint gait analysis -Immunohistochemical analyses report H-score quantification of BDNF, cleaved caspase-3, and IL-1β in dorsal root ganglia and sciatic nerve tissues. Excel files contain raw and processed values for statistical analysis across prophylactic and therapeutic protocols, comparing cenobamate with cisplatin-only and gabapentin-treated control groups.

创建时间:
2026-04-15
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