rs7574865 association with phenotype status of cases in homogeneous subset (n = 751) and multivariate analyses.

§See Table 1 for phenotype definitions.
Mantel-Haenzel odds ratio (OR) and p-value combined across cohorts.
Multivariate logistic regression adjusting for sex; ancestry as a categorical variable (90% or greater Northern European, 90% or greater European but <90% Northern European, not 90% or greater European); and disease duration for all outcomes except age of diagnosis.
‡UCSF and ABCoN only (see definitions Table 1): homogeneous n = 461, multivariate n = 790.
†First principal component of phenotypes (see Methods).