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资源简介：
Genome-wide analysis of p53 binding protein
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创建时间：
2014-04-01
相关数据集
Stress-dependent CHIP/Daxx interaction suppresses the p53 apoptotic program. Mus musculus
Our previous studies have implicated CHIP as a co-chaperone/ubiquitin ligase, whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-depende
NIAID Data Ecosystem60
Comparison of tumor spectrum in Mdm2+/+ and Mdm2+/− mice with deficiencies in Arf and/or p53.
Percentages were calculated from the total number of mice analyzed; – indicates no tumors of that type; F = female, M = male.
Figshare2015-12-02 更新20
Percentage of identity matrix of p53 proteins.
The identity matrix values were obtained using the Clustal Omega tool (https://www.ebi.ac.uk/Tools/msa/clustalo/) based on the full length sequence (A); the DBD (B); the N-terminal region (C) or the C
Figshare2015-12-03 更新10
p53 amyloid formation induced cellular transformation and tumor formation in xenograft model
p53 mutation and its subsequent loss of function along with gain of oncogenic functions is associated with cancer. However, the exact mechanism of how altered p53 acts as an oncogene is not clear yet.
NIAID Data Ecosystem50
Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status
Sirtuins (SIRT) belonging to the NAD+ dependent histone deacetylase III class of enzymes have emerged as master regulators of metabolism and longevity. However, their role in prevention of organismal
DataCite Commons2020-09-04 更新20
