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Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor

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Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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Complex Structure of Insulin-like Growth Factor Receptor and 3-Cyanoquinoline Inhibitor Descriptor: 4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile, Insulin-like growth factor 1 receptor Authors: Xu, W, Miller, L.M, Mayer, S.C, Berger, D.M, Boschelli, D.H, Boschelli, F. Deposit date: 2008-11-04 Release date: 2008-12-30 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment Bioorg.Med.Chem.Lett., 19, 2009
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2008-11-04
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