Additional file 7 of Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML

Additional file 7: Table S6. Upstream regulators and biological functions enriched by the 117 DEGs in pre-therapy HSC-like between resistant and sensitive groups using Ingenuity Pathway Analysis (IPA). Only those upstream regulators had an overlap p value of < 0.05 and a predicted activation state (activated or inhibited, with a z-score > 1.5 or < -1.5) were shown. Up- and downregulation of particular molecules were specified by red and blue arrows respectively. The front color indicated their predicted regulator activation state.