Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with fragment 820, NADPH, dUMP
收藏Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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https://pdbj.org/mine/summary/7ctw
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Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with fragment 820, NADPH, dUMP Descriptor: 1-(2-methylsulfanylphenyl)piperazine, Bifunctional dihydrofolate reductase-thymidylate synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Vanichtanankul, J, Vitsupakorn, D. Deposit date: 2020-08-20 Release date: 2021-04-28 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Discovery of new non-pyrimidine scaffolds as Plasmodium falciparum DHFR inhibitors by fragment-based screening. J Enzyme Inhib Med Chem, 36, 2021
创建时间：
2020-08-20
