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Epistasis in a fitness landscape defined by antibody-antigen binding free energy

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Mendeley Data2026-04-18 收录
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Data and code used to generate figures for "Epistasis in a fitness landscape defined by antibody-antigen binding free energy". This code is correct at time of submission, but will be updated at https://github.com/rhys-m-adams/epistasis_4_4_20 This code attempts to quantify the level of epistasis in CDR1H and CDR3H domains of the 4-4-20 fluorescein binding antibody. The readme details how to run the code, but briefly, install python 3.6, pymol as a command line argument, Numpy, scipy, matplotlib, emcee, cvxopt, svgutils, and pybeeswarm, then run the make_figs.sh script.
创建时间:
2018-12-17
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