Neutralization sensitivities of Env clones and site-directed mutants to autologous plasma and monoclonal antibodies.

aNeutralization sensitivity determined in TZM assay using autologous plasma starting at 1∶20 dilution and reported as the IC50 titer. Each value represents the mean (± standard deviation) of at least three independent experiments. For calculating means and standard deviations, IC50<20 were counted as 10.
*p<0.05, when mutant titers were compared with the T/F titer by two-tailed t-test.
bNeutralization sensitivity to autologous monoclonal antibodies (AbCH83 and AbCH84) from day 132 B-cells starting at a concentration of 10 ug/ml and reported in ug/ml IC50. Each value is the mean of at least three independent experiments.