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Development of Positive Selectable Markers for the Fungal Pathogen Cryptococcus neoformans

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC95837/
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Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in ∼10% of patients with AIDS. New selectable markers which confer resistance to G418 or phleomycin when transformed into C. neoformans were made. A hygromycin-selectable marker was modified to allow selection with a single copy of the marker.
提供机构:
American Society for Microbiology (ASM)
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