Additional file 1: of The cell surface mucin podocalyxin regulates collective breast tumor budding

Is Figure S1 showing podocalyxin has little effect on subcutaneous tumor size a or proliferation in monolayer culture b, Figure S2 showing podocalyxin overexpression promotes local invasion of MCF-7 tumor cell xenografts,. Figure S3 showing that the ezrin inhibitor NSC668394 disrupts apical podocalyxin localization in monolayer culture, Figure S4 showing normal mammary epithelial cells continue to form spheres and form single, polarized lumens in 3-D culture, and Figure S5 showing podocalyxin expression increases EGF-mediated signaling. (ZIP 1056 kb)