Pth1r
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=3442
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资源简介:
ENCODES a protein that exhibits parathyroid hormone receptor activity; peptide hormone binding; protein homodimerization activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; parathyroid hormone signaling pathway; G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH hypercalcemia; brachydactyly type E1 (ortholog); chondrodysplasia Blomstrand type (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; brush border membrane; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
编码一种表现出甲状旁腺激素受体活性的蛋白质;肽激素结合;蛋白质同源二聚化活性(同源);参与腺苷酸环化酶激活的G蛋白偶联受体信号通路;腺苷酸环化酶调节的G蛋白偶联受体信号通路;与环核苷酸第二信使偶联的G蛋白偶联受体信号通路;通过Galphaq家族介导的G蛋白信号通路参与;甲状旁腺激素信号通路;通过Galphas家族介导的G蛋白信号通路;与高钙血症相关;短指(E1型,同源);Blomstrand型软骨发育不全(同源);存在于顶膜;基底膜;刷状缘膜;与(+)-五味子素B、17β-雌二醇、2,3,7,8-四氯二苯并-对-氧杂芑(TCDD)相互作用。
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rgd.mcw.edu



