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Design and Synthesis of Thiophene Dihydroisoquinolins as Novel BACE-1 Inhibitors

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Design and Synthesis of Thiophene Dihydroisoquinolins as Novel BACE-1 Inhibitors Descriptor: Beta-secretase 1, N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-(4-propylthiophen-3-yl)-L-alanine, ZINC ION Authors: Yao, N, Brecht, E. Deposit date: 2012-11-16 Release date: 2013-10-09 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
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2012-11-16
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