Parameter values and 95% confidence intervals of the best-fit models SMT1≠R1, AM4, and CM4.

Note that parameter values marked with * were fixed due to previous assumptions (time delay parameters: ), fixed after sensitivity/identifiability analysis (μR) and personal communication (μV) (see Methods). The degradation rate of HCV RNA within the RC was set to μR = 0 as was the rate of degradation of intracellular virus μA = 0 (see main text). For parameter identifiability profiles see S3, S4 and S5 Figs.