Data accompanying "A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis"

brain_module_enrichment.csv : contains statistics from an anRichment anaylsis on all co-expression modules identified via WGCNA in brain samples (for Figure 7C)

brain_upregulated_module_enrichment_collapsed.csv : contains anRichment output from the gene list assembled by aggregating all 3 upregulated modules in brain samples (for Figure 6C)

brain_wgcna_results.csv : contains gene-level information for all genes in all brain regions, including gene-trait correlations and module membership statistics (for Figure 6B; this is Supplemental File 2 in the paper)

colon_module_enrichment.csv : contains anRichment output from all co-expression modules identified via WGCNA in our colon samples (for Figure 2)

colon_wgcna_results.csv : contains gene-level information for all genes in both colon regions (this is Supplemental File 1 in the paper)

raw_data.xlsx : contains raw tabular data for non-sequencing analyses in the paper, spanning several main and supplementary figures

All other files are from a DESeq2 analysis in each brain region at each time point in our study. The names of those files describe which region (the first field of the name) is being examined, and what time point (the second field of the name) is being compared to our 0d control time point. 

Most of these data, especially output from RNA sequencing data, can be recreated by following the code at https://github.com/jakesboles/Boles_et-al_DSS_time-series.