QSAR Modeling Data of 2-Aminothiazol-4(5H)-One Derivatives as 11β-HSD1 Inhibitors

This dataset supports the manuscript entitled "Computational QSAR Study of Novel 2-Aminothiazol-4(5H)-One Derivatives as 11β‐HSD1 Inhibitors". It contains molecular structures, descriptor values, and experimental 11β-HSD1 inhibitory activities of 56 synthesized 2-aminothiazol-4(5H)-one derivatives and structures and descriptor values of 39 newly designed analogs. Molecular descriptors were calculated using Dragon 7.0 after DFT optimization with Gaussian 16. The data are intended to ensure the QSAR model's reproducibility and enable reuse in related cheminformatics or drug discovery projects.