Crystal structure of human anaplastic lymphoma kinase in complex with piperidine-carboxamide inhibitor 2
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Crystal structure of human anaplastic lymphoma kinase in complex with piperidine-carboxamide inhibitor 2 Descriptor: (3S)-N-[3-(trifluoromethoxy)benzyl]-1-{2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}piperidine-3-carboxamide, ALK tyrosine kinase receptor Authors: Whittington, D.A, Epstein, L.F, Chen, H. Deposit date: 2012-06-20 Release date: 2012-08-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.6 Å) Cite: The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. J.Biol.Chem., 287, 2012
创建时间：
2012-06-20
